Modelling Immune System Processes

Established: June 1, 2009

Publications

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- A theory for how the antigen presentation profile influences the timing of T-cell detection
  
  Alberto Carignano, Neil Dalchau
  
  November 2018
  
  bioRxiv | November 2018
  
  Publication
- A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules
  
  Denise S. M. Boulanger, Ruth C. Eccleston, Andrew Phillips, Peter V. Coveney, T. Elliott, Neil Dalchau
  
  Frontiers in Immunology | July 2018, Vol 9: pp. 1538
  
  Publication Publication Project
- Host genotype and time dependent antigen presentation of viral peptides: predictions from theory
  
  Ruth Charlotte Eccleston, Peter V. Coveney, Neil Dalchau
  
  Scientific Reports | October 2017, Vol 7: pp. 14367
  
  Publication Publication Project
- The Role of Multiscale Protein Dynamics in Antigen Presentation and T Lymphocyte Recognition
  
  Ruth Charlotte Eccleston, Shunzhou Wan, Neil Dalchau, Peter V. Coveney
  
  Frontiers in Immunology | July 2017
  
  Publication DOI PDF Project
- Selector function of MHC I molecules is determined by protein plasticity
  
  Alistair Bailey, Neil Dalchau, Rachel Carter, Stephen Emmott, Andrew Phillips, Jörn M. Werner, Tim Elliott
  
  Scientific Reports | October 2015, Vol 5: pp. 14928
  
  Publication Publication Project
- A peptide filtering relation quantifies MHC class I peptide optimization
  
  Neil Dalchau, Andrew Phillips, Leonard D Goldstein, Mark Howarth, Luca Cardelli, Stephen Emmott, Tim Elliott, Joern M Werner
  
  PLoS Computational Biology | October 2011, Vol 7(10): pp. e1002144
  
  Publication Publication Project Project
- The cell biology of major histocompatibility complex class I assembly: towards a molecular understanding
  
  Andy van Hateren, Ed James, Alistair Bailey, Andrew Phillips, Neil Dalchau, Tim Elliott
  
  Tissue Antigens | October 2010, Vol 76(4): pp. 259
  
  PDF Publication Project

- A theory for how the antigen presentation profile influences the timing of T-cell detection
  
  Alberto Carignano, Neil Dalchau
  
  November 2018
  
  bioRxiv | November 2018
  
  Publication
- A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules
  
  Denise S. M. Boulanger, Ruth C. Eccleston, Andrew Phillips, Peter V. Coveney, T. Elliott, Neil Dalchau
  
  Frontiers in Immunology | July 2018, Vol 9: pp. 1538
  
  Publication Publication Project
- Host genotype and time dependent antigen presentation of viral peptides: predictions from theory
  
  Ruth Charlotte Eccleston, Peter V. Coveney, Neil Dalchau
  
  Scientific Reports | October 2017, Vol 7: pp. 14367
  
  Publication Publication Project
- The Role of Multiscale Protein Dynamics in Antigen Presentation and T Lymphocyte Recognition
  
  Ruth Charlotte Eccleston, Shunzhou Wan, Neil Dalchau, Peter V. Coveney
  
  Frontiers in Immunology | July 2017
  
  Publication DOI PDF Project
- The cell biology of major histocompatibility complex class I assembly: towards a molecular understanding
  
  Andy van Hateren, Ed James, Alistair Bailey, Andrew Phillips, Neil Dalchau, Tim Elliott
  
  Tissue Antigens | October 2010, Vol 76(4): pp. 259
  
  PDF Publication Project
- Selector function of MHC I molecules is determined by protein plasticity
  
  Alistair Bailey, Neil Dalchau, Rachel Carter, Stephen Emmott, Andrew Phillips, Jörn M. Werner, Tim Elliott
  
  Scientific Reports | October 2015, Vol 5: pp. 14928
  
  Publication Publication Project
- A peptide filtering relation quantifies MHC class I peptide optimization
  
  Neil Dalchau, Andrew Phillips, Leonard D Goldstein, Mark Howarth, Luca Cardelli, Stephen Emmott, Tim Elliott, Joern M Werner
  
  PLoS Computational Biology | October 2011, Vol 7(10): pp. e1002144
  
  Publication Publication Project Project

- A theory for how the antigen presentation profile influences the timing of T-cell detection
  
  Alberto Carignano, Neil Dalchau
  
  November 2018
  
  bioRxiv | November 2018
  
  Publication
- A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules
  
  Denise S. M. Boulanger, Ruth C. Eccleston, Andrew Phillips, Peter V. Coveney, T. Elliott, Neil Dalchau
  
  Frontiers in Immunology | July 2018, Vol 9: pp. 1538
  
  Publication Publication Project
- Host genotype and time dependent antigen presentation of viral peptides: predictions from theory
  
  Ruth Charlotte Eccleston, Peter V. Coveney, Neil Dalchau
  
  Scientific Reports | October 2017, Vol 7: pp. 14367
  
  Publication Publication Project
- The Role of Multiscale Protein Dynamics in Antigen Presentation and T Lymphocyte Recognition
  
  Ruth Charlotte Eccleston, Shunzhou Wan, Neil Dalchau, Peter V. Coveney
  
  Frontiers in Immunology | July 2017
  
  Publication DOI PDF Project
- Selector function of MHC I molecules is determined by protein plasticity
  
  Alistair Bailey, Neil Dalchau, Rachel Carter, Stephen Emmott, Andrew Phillips, Jörn M. Werner, Tim Elliott
  
  Scientific Reports | October 2015, Vol 5: pp. 14928
  
  Publication Publication Project
- A peptide filtering relation quantifies MHC class I peptide optimization
  
  Neil Dalchau, Andrew Phillips, Leonard D Goldstein, Mark Howarth, Luca Cardelli, Stephen Emmott, Tim Elliott, Joern M Werner
  
  PLoS Computational Biology | October 2011, Vol 7(10): pp. e1002144
  
  Publication Publication Project Project
- The cell biology of major histocompatibility complex class I assembly: towards a molecular understanding
  
  Andy van Hateren, Ed James, Alistair Bailey, Andrew Phillips, Neil Dalchau, Tim Elliott
  
  Tissue Antigens | October 2010, Vol 76(4): pp. 259
  
  PDF Publication Project

Modelling Immune System Processes

Publications

A theory for how the antigen presentation profile influences the timing of T-cell detection

A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules

Host genotype and time dependent antigen presentation of viral peptides: predictions from theory

The Role of Multiscale Protein Dynamics in Antigen Presentation and T Lymphocyte Recognition

Selector function of MHC I molecules is determined by protein plasticity

A peptide filtering relation quantifies MHC class I peptide optimization

The cell biology of major histocompatibility complex class I assembly: towards a molecular understanding

A theory for how the antigen presentation profile influences the timing of T-cell detection

A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules

Host genotype and time dependent antigen presentation of viral peptides: predictions from theory

The Role of Multiscale Protein Dynamics in Antigen Presentation and T Lymphocyte Recognition

The cell biology of major histocompatibility complex class I assembly: towards a molecular understanding

Selector function of MHC I molecules is determined by protein plasticity

A peptide filtering relation quantifies MHC class I peptide optimization

A theory for how the antigen presentation profile influences the timing of T-cell detection

A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules

Host genotype and time dependent antigen presentation of viral peptides: predictions from theory

The Role of Multiscale Protein Dynamics in Antigen Presentation and T Lymphocyte Recognition

Selector function of MHC I molecules is determined by protein plasticity

A peptide filtering relation quantifies MHC class I peptide optimization

The cell biology of major histocompatibility complex class I assembly: towards a molecular understanding